Journal Reviews

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Differentiating orbital cellulitis from non-specific orbital inflammation

4 December 2023 | | Oculoplastics, Orbit | C-Reactive protein, Non-specific orbital inflammation, inflammatory markers, orbital cellulitis, white-cell count

This is a retrospective study looking at whether common laboratory investigations can help differentiate between orbital cellulitis (OC) and non-specific orbital inflammation (NSOI). NSOI is a diagnosis of exclusion following negative investigations for systemic diseases such as IgG4-related disease, granulomatosis...

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Orbital manifestations of granulomatosis with polyangitis

4 February 2021 | | Oculoplastics, Orbit | Granulomatosis with polyangiitis, Orbital granulomatosis, Wegener disease, orbital inflammation, orbital tumors

This a retrospective, observational study where authors looked at the ophthalmological examination, biopsy, antibodies and CT scan results of all patients diagnosed with granulomatosis with polyangitis (GPA) from January 2007-January 2019. Out of 101 patients with diagnosis of GPA, 15...

IgG4 related orbital disease

1 June 2018 | | Oculoplastics, Orbit | IgG4-related orbital disease, lymphoma, nonspecific orbital inflammation, orbit

This retrospective study was done to determine the prevalence of IgG4 related orbital disease (IgG4ROD) in patients who previously had biopsies for suspected idiopathic orbital inflammatory disease (IOID) and / or orbital lymphoproliferative disease (OLD). The charts and slides of...

Bisphosphonates can cause orbital inflammation

1 April 2016 | | Neuro-Ophthalmology | Bisphosphonate, complication, orbital inflammation, orbital inflammatory syndrome, side effect, zolendronate

The authors describe four patients with bisphosphonate induced orbital inflammation and review a further 25 cases in the literature. Intravenous zoledronate was the most common precipitant (76% of cases) with the mean time until onset of inflammation being three days...